| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CEP192-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | CEP192 |
| Gene ID: | 55125 |
| Uniprot ID: | CE192_HUMAN |
| Immunogen Region: | Ser1764-Ile2010 |
| Immunogen: | Homo sapiens (Human) |
| Function | Required for mitotic centrosome maturation and bipolar spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Centrosome-specific activating scaffold for AURKA and PLK1. |
| Protein Name | Centrosomal Protein Of 192 KdaCep192Cep192/Spd-2 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentriolePericentriolar Location In Mitotic Centrosomes |
| Alternative Protein Names | Centrosomal Protein Of 192 Kda proteinCep192 proteinCep192/Spd-2 proteinCEP192 proteinKIAA1569 proteinPP8407 protein |
Information sourced from Uniprot.org