| Host: |
E.coli |
| Applications: |
SDS-PAGE/Denatured |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Recombinant-Human CENPP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: |
Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Concentration: |
1 mg/mL |
| Storage Instruction: |
For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CENPP |
| Gene ID: |
401541 |
| Uniprot ID: |
CENPP_HUMAN |
| Immunogen Region: |
1-288aa |
| Accession Number: |
NP_001012267 |
| Immunogen: |
Human |
| Immunogen Sequence: |
MDAELAEVRA LQAEIAALRR ACEDPPAPWE EKSRVQKSFQ AIHQFNLEGW KSSKDLKNQL GHLESELSFL STLTGINIRN HSKQTEDLTS TEMTEKSIRK VLQRHRLSGN CHMVTFQLEF QILEIQNKER LSSAVTDLNI IMEPTECSEL SEFVSRAEER KDLFMFFRSL HFFVEWFEYR KRTFKHLKEK YPDAVYLSEG PSSCSM |
| Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. |
| Protein Name | Centromere Protein PCenp-P |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-606279Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusChromosomeCentromereLocalizes Exclusively In The CentromeresThe Cenpa-Cad Complex Is Probably Recruited On Centromeres By The Cenpa-Nac Complex |
| Alternative Protein Names | Centromere Protein P proteinCenp-P proteinCENPP protein |
Information sourced from Uniprot.org
