| Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone. |
| Protein Name | Centromere Protein ICenp-IFsh Primary Response Protein 1Follicle-Stimulating Hormone Primary Response ProteinInterphase Centromere Complex Protein 19Leucine-Rich Primary Response Protein 1 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-606279Reactome: R-HSA-68877Reactome: R-HSA-9648025 |
| Cellular Localisation | NucleusChromosomeCentromereLocalizes Exclusively In The CentromeresThe Cenpa-Cad Complex Is Probably Recruited On Centromeres By The Cenpa-Nac Complex |
| Alternative Protein Names | Centromere Protein I proteinCenp-I proteinFsh Primary Response Protein 1 proteinFollicle-Stimulating Hormone Primary Response Protein proteinInterphase Centromere Complex Protein 19 proteinLeucine-Rich Primary Response Protein 1 proteinCENPI proteinFSHPRH1 proteinICEN19 proteinLRPR1 protein |
Information sourced from Uniprot.org
