| Post Translational Modifications | Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. |
| Protein Name | Cell Adhesion Molecule Ceacam5Carcinoembryonic AntigenCeaCarcinoembryonic Antigen-Related Cell Adhesion Molecule 5Cea Cell Adhesion Molecule 5Meconium Antigen 100Cd Antigen Cd66e |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorApical Cell MembraneCell SurfaceLocalized To The Apical Glycocalyx Surface |
| Alternative ELISA Names | Cell Adhesion Molecule Ceacam5 ELISA kitCarcinoembryonic Antigen ELISA kitCea ELISA kitCarcinoembryonic Antigen-Related Cell Adhesion Molecule 5 ELISA kitCea Cell Adhesion Molecule 5 ELISA kitMeconium Antigen 100 ELISA kitCd Antigen Cd66e ELISA kitCEACAM5 ELISA kitCEA ELISA kit |
| Specificity | This kit recognizes Human CEA in samples. No significant cross-reactivity or interference between Human CEA and analogues was observed. |
| Reproducibility | Both intra-CV and inter-CV are |
Information sourced from Uniprot.org
| Item | Specifications | Storage |
| Micro ELISA Plate (Dismountable) | 96T: 8 wells ×12 strips strips | -20℃, 6 months |
| Reference Standard | 96T: 2 vials 48T: 1 vial | -20℃, 6 months |
| Concentrated Biotinylated Detection Ab (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃, 6 months |
| Concentrated HRP Conjugate (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃ (Protect from light), 6 months |
| Reference Standard & Sample Diluent | 1 vial, 20 mL | 2-8°C, 6 months |
| Biotinylated Detection Ab Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
| HRP Conjugate Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
| Concentrated Wash Buffer (25×) | 1 vial, 30 mL | 2-8°C, 6 months |
| Substrate Reagent | 1 vial, 10 mL | 2-8℃ (Protect from light) |
| Stop Solution | 1 vial, 10 mL | 2-8°C |
| Plate Sealer | 5 pieces | |
| Manual | 1 copy | |
| Certificate of Analysis | 1 copy | |
| Sample Type | Range (%) | Average Recovery (%) |
| Serum(n=8) | 93-104 | 96 |
| EDTA plasma (n=8) | 93-103 | 96 |
| Cell culture media (n=8) | 92-101 | 95 |
| | Intra-assay Precision | Intra-assay Precision | Intra-assay Precision | Inter-assay Precision | Inter-assay Precision | Inter-assay Precision |
| Sample | 1.00 | 2.00 | 3.00 | 1.00 | 2.00 | 3.00 |
| n | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 |
| Mean (ng/mL) | 0.49 | 1.20 | 4.32 | 0.50 | 1.04 | 4.59 |
| Standard deviation | 0.03 | 0.06 | 0.18 | 0.03 | 0.05 | 0.19 |
| CV (%) | 6.12 | 5.00 | 4.17 | 6.00 | 4.81 | 4.14 |
