Human CDC25B protein (Recombinant) (N-His) (STJP004524)

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STJP004524
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CDC25B-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CDC25B
Gene ID: 994
Uniprot ID: MPIP2_HUMAN
Immunogen Region: Cys377-Gly566
Immunogen: Homo sapiens (Human)
Function Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. The three isoforms seem to have a different level of activity.
Protein Name M-Phase Inducer Phosphatase 2
Dual Specificity Phosphatase Cdc25b
Database Links Reactome: R-HSA-69273
Reactome: R-HSA-69656
Reactome: R-HSA-8862803
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle Pole
Alternative Protein Names M-Phase Inducer Phosphatase 2 protein
Dual Specificity Phosphatase Cdc25b protein
CDC25B protein
CDC25HU2 protein

Information sourced from Uniprot.org

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