Human CD88/C5AR1 protein (Recombinant) (N-His-SUMO) (STJP008877)

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STJP008877
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD88/C5AR1-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: C5AR1
Gene ID: 728
Uniprot ID: C5AR1_HUMAN
Immunogen Region: Arg175-Arg206
Immunogen: Homo sapiens (Human)
Function Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
Protein Name C5a Anaphylatoxin Chemotactic Receptor 1
C5a Anaphylatoxin Chemotactic Receptor
C5a-R
C5ar
Cd Antigen Cd88
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Reactome: R-HSA-977606
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Phosphorylated C5ar Colocalizes With Arrb1 And Arrb2 In Cytoplasmic Vesicles
Alternative Protein Names C5a Anaphylatoxin Chemotactic Receptor 1 protein
C5a Anaphylatoxin Chemotactic Receptor protein
C5a-R protein
C5ar protein
Cd Antigen Cd88 protein
C5AR1 protein
C5AR protein
C5R1 protein

Information sourced from Uniprot.org