Human CD83 protein (Recombinant) (N-GST) (STJP005121)

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STJP005121
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD83-N-GST protein was developed from e.coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CD83
Gene ID: 9308
Uniprot ID: CD83_HUMAN
Immunogen Region: Lys24-Val205
Immunogen: Homo sapiens (Human)
Post Translational Modifications Glycosylated when expressed on activated dendritic cells.
Function Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHCII trafficking MARCHF8. Also inhibits MARCHF1 association with MHCII or CD86 to prevent their ubiquitination and subsequent degradation. In addition, acts as an important modulator of protective responses against acute infections.
Protein Name Cd83 Antigen
Hcd83
B-Cell Activation Protein
Cell Surface Protein Hb15
Cd Antigen Cd83
Database Links
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Cd83 Antigen protein
Hcd83 protein
B-Cell Activation Protein protein
Cell Surface Protein Hb15 protein
Cd Antigen Cd83 protein
CD83 protein

Information sourced from Uniprot.org

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