| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.001 EU/Mu g |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human CD7 Protein at 2 Mu g/mL (100 Mu L/well) can bind human SECTM1 with a linear range of 0.098-1.3 ng/mL. |
| Gene Symbol: | CD7 |
| Gene ID: | 924 |
| Uniprot ID: | CD7_HUMAN |
| Immunogen Region: | Ala26-Pro180 |
| Immunogen: | Recombinant Human CD7 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala26-Pro180) of human CD7 (Accession #NP_006128.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | AQEVQQSPHCTTVPVGASVN ITCSTSGGLRGIYLRQLGPQ PQDIIYYEDGVVPTTDRRFR GRIDFSGSQDNLTITMHRLQ LSDTGTYTCQAITEVNVYGS GTLVLVTEEQSQGWHRCSDA PPRASALPAPPTGSALPDPQ TASALPDPPAASALP |
| Function | Transmembrane glycoprotein expressed by T-cells and natural killer (NK) cells and their precursors. Plays a costimulatory role in T-cell activation upon binding to its ligand K12/SECTM1. In turn, mediates the production of cytokines such as IL-2. On resting NK-cells, CD7 activation results in a significant induction of interferon-gamma levels. |
| Protein Name | T-Cell Antigen Cd7Gp40T-Cell Leukemia AntigenT-Cell Surface Antigen Leu-9Tp41Cd Antigen Cd7 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | T-Cell Antigen Cd7 proteinGp40 proteinT-Cell Leukemia Antigen proteinT-Cell Surface Antigen Leu-9 proteinTp41 proteinCd Antigen Cd7 proteinCD7 protein |
Information sourced from Uniprot.org