Human CD66e/CEA/CEACAM5 protein (Recombinant) (N-His) (STJP003753)

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STJP003753
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD66e/CEA/CEACAM5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CEACAM5
Gene ID: 1048
Uniprot ID: CEAM5_HUMAN
Immunogen Region: Ala34-Leu234
Immunogen: Homo sapiens (Human)
Post Translational Modifications Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
Function Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression.induces resistance to anoikis of colorectal carcinoma cells. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Protein Name Cell Adhesion Molecule Ceacam5
Carcinoembryonic Antigen
Cea
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5
Cea Cell Adhesion Molecule 5
Meconium Antigen 100
Cd Antigen Cd66e
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Protein Names Cell Adhesion Molecule Ceacam5 protein
Carcinoembryonic Antigen protein
Cea protein
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 protein
Cea Cell Adhesion Molecule 5 protein
Meconium Antigen 100 protein
Cd Antigen Cd66e protein
CEACAM5 protein
CEA protein

Information sourced from Uniprot.org

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