Human CD50/ICAM3 protein (Recombinant-Active) (C-hFc-His) (STJP011970)

SKU:
STJP011970-100
£553.50
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD50/ICAM3-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: ICAM3
Gene ID: 3385
Uniprot ID: ICAM3_HUMAN
Immunogen Region: Gln30-His485
Immunogen: Homo sapiens (Human)
Post Translational Modifications Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated.glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages.
Protein Name Intercellular Adhesion Molecule 3
Icam-3
Cdw50
Icam-R
Cd Antigen Cd50
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-5621575
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Intercellular Adhesion Molecule 3 protein
Icam-3 protein
Cdw50 protein
Icam-R protein
Cd Antigen Cd50 protein
ICAM3 protein

Information sourced from Uniprot.org