Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human CD42d/GP5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | GP5 |
Gene ID: | 2814 |
Uniprot ID: | GPV_HUMAN |
Immunogen Region: | Gln17-Pro242 |
Immunogen: | Homo sapiens (Human) |
Post Translational Modifications | The N-terminus is blocked. |
Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. |
Protein Name | Platelet Glycoprotein VGpvGlycoprotein 5Cd Antigen Cd42d |
Database Links | Reactome: R-HSA-140837Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-9673221Reactome: R-HSA-9845620Reactome: R-HSA-9846298 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Platelet Glycoprotein V proteinGpv proteinGlycoprotein 5 proteinCd Antigen Cd42d proteinGP5 protein |
Information sourced from Uniprot.org