Human CD39L2/ENTPD6 protein (Recombinant) (His-Tag) (STJP018891)

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STJP018891
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD39L2/ENTPD6-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: ENTPD6
Gene ID: 955
Uniprot ID: ENTP6_HUMAN
Immunogen Region: 61-484aa
Accession Number: NP_001238
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSKWHRATA TQAFFSITRA APGARWGQQA HSPLGTAADG HEVFYGIMFD AGSTGTRVHV FQFTRPPRET PTLTHETFKA LKPGLSAYAD DVEKSAQGIR ELLDVAKQDI PFDFWKATPL VLKATAGLRL LPGEKAQKLL QKVKEVFKAS PFLVGDDCVS IMNGTDEGVS AWITINFLTG SLKTPGGSSV GMLDLGGGST QIAFLPRV
Tissue Specificity Expressed in most tissues, but predominantly in heart.
Post Translational Modifications The secreted form may be produced by intracellular processing. N-glycosylated.
Function Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP. The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides.
Protein Name Ectonucleoside Triphosphate Diphosphohydrolase 6
Ntpdase 6
Cd39 Antigen-Like 2
Database Links Reactome: R-HSA-8850843
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Cell Membrane
Exists As A Secreted And Membrane-Bound Forms In The Medium Of Transfected Cells
The Secreted Form Is Predominant
Alternative Protein Names Ectonucleoside Triphosphate Diphosphohydrolase 6 protein
Ntpdase 6 protein
Cd39 Antigen-Like 2 protein
ENTPD6 protein
CD39L2 protein
IL6ST2 protein

Information sourced from Uniprot.org

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