Human CD39L2/ENTPD6 protein (Recombinant) (His-Tag) (STJP018891)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CD39L2/ENTPD6-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ENTPD6 |
| Gene ID | 955 |
| Uniprot ID | ENTP6_HUMAN |
| Accession Number | NP_001238 |
| Immunogen | Human |
| Immunogen Region | 61-484aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSKWHRATA TQAFFSITRA APGARWGQQA HSPLGTAADG HEVFYGIMFD AGSTGTRVHV FQFTRPPRET PTLTHETFKA LKPGLSAYAD DVEKSAQGIR ELLDVAKQDI PFDFWKATPL VLKATAGLRL LPGEKAQKLL QKVKEVFKAS PFLVGDDCVS IMNGTDEGVS AWITINFLTG SLKTPGGSSV GMLDLGGGST QIAFLPRV |
Additional Info
| Tissue Specificity | Expressed in most tissues, but predominantly in heart. |
| Post Translational Modifications | The secreted form may be produced by intracellular processing. N-glycosylated. |
| Function | Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP. The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 6Ntpdase 6Cd39 Antigen-Like 2 |
| Database Links | Reactome: R-HSA-8850843 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedCell MembraneExists As A Secreted And Membrane-Bound Forms In The Medium Of Transfected CellsThe Secreted Form Is Predominant |
| Alternative Protein Names | Ectonucleoside Triphosphate Diphosphohydrolase 6 proteinNtpdase 6 proteinCd39 Antigen-Like 2 proteinENTPD6 proteinCD39L2 proteinIL6ST2 protein |
Information sourced from Uniprot.org