Human CD39/ENTPD1 protein (Recombinant) (N-His) (STJP004844)

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STJP004844
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD39/ENTPD1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ENTPD1
Gene ID: 953
Uniprot ID: ENTP1_HUMAN
Immunogen Region: Met1-Tyr340
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. The N-terminus is blocked. Palmitoylated on Cys-13.which is required for caveola targeting.
Function Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.
Protein Name Ectonucleoside Triphosphate Diphosphohydrolase 1
Atp Diphosphohydrolase
Atp-Dph
Atpdase
Ecto-Atp Diphosphohydrolase 1
Ecto-Atpdase 1
Ecto-Atpase 1
Ecto-Apyrase
Lymphoid Cell Activation Antigen
Nucleoside Triphosphate Diphosphohydrolase 1
Ntpdase1
Cd Antigen Cd39
Database Links Reactome: R-HSA-8850843
Reactome: R-HSA-9660826
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Caveola
Alternative Protein Names Ectonucleoside Triphosphate Diphosphohydrolase 1 protein
Atp Diphosphohydrolase protein
Atp-Dph protein
Atpdase protein
Ecto-Atp Diphosphohydrolase 1 protein
Ecto-Atpdase 1 protein
Ecto-Atpase 1 protein
Ecto-Apyrase protein
Lymphoid Cell Activation Antigen protein
Nucleoside Triphosphate Diphosphohydrolase 1 protein
Ntpdase1 protein
Cd Antigen Cd39 protein
ENTPD1 protein
CD39 protein

Information sourced from Uniprot.org