Human CD350/FZD10 protein (Recombinant) (C-hFc) (STJP012779)

Name: Human CD350/FZD10 protein (Recombinant) (C-hFc) (STJP012779)
SKU: STJP012779-100
Price: 648.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP012779-100

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human CD350/FZD10-C-hFc protein was developed from mammalian cells and has a target region of C-hFc. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Ubiquitinated by ZNRF3, leading to its degradation by the proteasome.
Function	Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
Protein Name	Frizzled-10 Fz-10 Hfz10 Fze7 Cd Antigen Cd350
Database Links	Reactome: R-HSA-373080
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Protein Names	Frizzled-10 protein Fz-10 protein Hfz10 protein Fze7 protein Cd Antigen Cd350 protein FZD10 protein

Information sourced from Uniprot.org