Human CD32b/FCGR2B protein (Recombinant-Active) (C-His) (STJP011967)

SKU:
STJP011967-100
£553.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD32b/FCGR2B-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: FCGR2B
Gene ID: 2213
Uniprot ID: FCG2B_HUMAN
Immunogen Region: Ala46-Pro217
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.
Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B
Igg Fc Receptor Ii-B
Cdw32
Fc-Gamma Rii-B
Fc-Gamma-Riib
Fcrii-B
Cd Antigen Cd32
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B protein
Igg Fc Receptor Ii-B protein
Cdw32 protein
Fc-Gamma Rii-B protein
Fc-Gamma-Riib protein
Fcrii-B protein
Cd Antigen Cd32 protein
FCGR2B protein
CD32 protein
FCG2 protein
IGFR2 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP007061 Human CD32b/FCGR2B protein (Recombinant) (C-His) (STJP007061) Mammalian Cells
STJP004555 Human CD32b/FCGR2B protein (Recombinant) (N-His) (STJP004555) E. coli
STJP000512 Human CD32b (FcgR2b) protein (Recombinant) (STJP000512) HEK293
STJP000206 Human CD32b (FcgR2b) protein (Recombinant) {Biotin} (STJP000206) HEK293 ELISA/WB
STJP000851 Human Fc-gamma RIIb/CD32b protein (Recombinant) (C-His) (STJP000851) HEK293 cells

Related Products

!