Human CD320 protein (Recombinant) (C-Fc) (STJP007138)

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STJP007138
£469.50 - £2,492.50
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD320-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CD320
Gene ID: 51293
Uniprot ID: CD320_HUMAN
Immunogen Region: Met1-Gly208
Immunogen: Homo sapiens (Human)
Function Receptor for transcobalamin saturated with cobalamin (TCbl). Plays an important role in cobalamin uptake. Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells. Functions as costimulator to promote B cell responses to antigenic stimuli.promotes B cell differentiation and proliferation. Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10.
Protein Name Cd320 Antigen
8d6 Antigen
Fdc-Signaling Molecule 8d6
Fdc-Sm-8d6
Transcobalamin Receptor
Tcblr
Cd Antigen Cd320
Database Links Reactome: R-HSA-3359485
Reactome: R-HSA-9758890
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Cd320 Antigen protein
8d6 Antigen protein
Fdc-Signaling Molecule 8d6 protein
Fdc-Sm-8d6 protein
Transcobalamin Receptor protein
Tcblr protein
Cd Antigen Cd320 protein
CD320 protein
8D6A protein
UNQ198 protein
PRO224 protein

Information sourced from Uniprot.org