| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.068ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This CD27BP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | SIVA1 |
| Gene ID: | 10572 |
| Uniprot ID: | SIVA_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon. |
| Post Translational Modifications | Phosphorylated by ABL2/ARG in response to oxidative stress. |
| Function | Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. |
| Protein Name | Apoptosis Regulatory Protein SivaCd27-Binding ProteinCd27bp |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusIn The NucleusAccumulates In Dot-Like Structures |
| Alternative ELISA Names | Apoptosis Regulatory Protein Siva ELISA kitCd27-Binding Protein ELISA kitCd27bp ELISA kitSIVA1 ELISA kitSIVA ELISA kit |
| output |
Information sourced from Uniprot.org
