Name: Human CD271/NGFR protein (Recombinant) (N-His) (STJP003822)
SKU: STJP003822
Availability: InStock

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human CD271/NGFR-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Gene Symbol:	NGFR
Gene ID:	4804
Uniprot ID:	TNR16_HUMAN
Immunogen Region:	Lys29-Asn250
Immunogen:	Homo sapiens (Human)

Function	Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Necessary for the circadian oscillation of the clock genes BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 16 Gp80-Lngfr Low Affinity Neurotrophin Receptor P75ntr Low-Affinity Nerve Growth Factor Receptor Ngf Receptor Low-Affinity Nerve Growth Factor Receptor P75ngfr Low-Affinity Nerve Growth Factor Receptor P75ngr P75 Icd Cd Antigen Cd271
Database Links	Reactome: R-HSA-193634 Reactome: R-HSA-193648 Reactome: R-HSA-193670 Reactome: R-HSA-193681 Reactome: R-HSA-193692 Reactome: R-HSA-205017 Reactome: R-HSA-205025 Reactome: R-HSA-205043 Reactome: R-HSA-209543 Reactome: R-HSA-209560 Reactome: R-HSA-209563
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Perikaryon Cell Projection Growth Cone Dendritic Spine
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 16 protein Gp80-Lngfr protein Low Affinity Neurotrophin Receptor P75ntr protein Low-Affinity Nerve Growth Factor Receptor protein Ngf Receptor protein Low-Affinity Nerve Growth Factor Receptor P75ngfr protein Low-Affinity Nerve Growth Factor Receptor P75ngr protein P75 Icd protein Cd Antigen Cd271 protein NGFR protein TNFRSF16 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP011821	Human CD271/NGFR protein (Recombinant-Active) (C-hFc-His) (STJP011821)	Mammalian Cells
STJP007019	Human CD271/NGFR protein (Recombinant) (C-Fc) (STJP007019)	Mammalian Cells
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP008089	Human SNX1 protein (Recombinant) (N-His) (STJP008089)	E. coli

Human CD271/NGFR protein (Recombinant) (N-His) (STJP003822)

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