Human CD258/TNFSF14/LIGHT protein (Recombinant) (N-His) (STJP003282)

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STJP003282
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD258/TNFSF14/LIGHT-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TNFSF14
Gene ID: 8740
Uniprot ID: TNF14_HUMAN
Immunogen Region: Asp74-Val240
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
Function Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 14
Herpes Virus Entry Mediator Ligand
Hvem-L
Herpesvirus Entry Mediator Ligand
Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5669034
Reactome: R-HSA-5676594
Cellular Localisation Tumor Necrosis Factor Ligand Superfamily Member 14
Membrane Form: Cell Membrane
Single-Pass Type Ii Membrane Protein
Soluble Form: Secreted
Isoform 2: Cytoplasm
Alternative Protein Names Tumor Necrosis Factor Ligand Superfamily Member 14 protein
Herpes Virus Entry Mediator Ligand protein
Hvem-L protein
Herpesvirus Entry Mediator Ligand protein
Cd Antigen Cd258 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 14 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 14 - Soluble Form protein
TNFSF14 protein
HVEML protein
LIGHT protein
UNQ391 protein
PRO726 protein

Information sourced from Uniprot.org

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