Human CD249 (ENPEP) protein (Recombinant) (STJP000594)

SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding Human extracellular domain of human CD249including a C-terminal 6His tag was expressed in HEK293 cells. NA
STJP000594
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General Information

Short DescriptionRecombinant-Human CD249 (ENPEP)-protein was developed from hek293. For use in research applications.
HostHEK293
NoteSTRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Formulation0.2 Mu m filtered PBS solution, pH7.2.
Storage InstructionCan be stored in working aliquots at 2ยฐC-8ยฐC C for one month, or at-20ยฐC to-70ยฐC for 1 year. Avoid repeated freeze/thaw cycles. NA
EndotoxinEndotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/ยตg (1EU/ยตg). NA

Target Information

Gene SymbolENPEP
Gene ID2028
Uniprot IDAMPE_HUMAN
ImmunogenOptimized DNA sequence encoding Human extracellular domain of human CD249including a C-terminal 6His tag was expressed in HEK293 cells. NA
Immunogen RegionECD

Additional Info

Tissue Specificity Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.
Function Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
Protein Name Glutamyl Aminopeptidase
Eap
Aminopeptidase A
Ap-A
Differentiation Antigen Gp160
Cd Antigen Cd249
Database Links Reactome: R-HSA-2022377
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Glutamyl Aminopeptidase protein
Eap protein
Aminopeptidase A protein
Ap-A protein
Differentiation Antigen Gp160 protein
Cd Antigen Cd249 protein
ENPEP protein

Information sourced from Uniprot.org

Citations

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