| Short Description : | Recombinant-Human CD249 (ENPEP)-protein was developed from hek293. For use in research applications. |
| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | 0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | ENPEP |
| Gene ID: | 2028 |
| Uniprot ID: | AMPE_HUMAN |
| Immunogen: | Optimized DNA sequence encoding Human extracellular domain of human CD249including a C-terminal 6His tag was expressed in HEK293 cells. NA |
| Immunogen Region: | ECD |
| Tissue Specificity | Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
| Function | Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. |
| Protein Name | Glutamyl AminopeptidaseEapAminopeptidase AAp-ADifferentiation Antigen Gp160Cd Antigen Cd249 |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Glutamyl Aminopeptidase proteinEap proteinAminopeptidase A proteinAp-A proteinDifferentiation Antigen Gp160 proteinCd Antigen Cd249 proteinENPEP protein |
Information sourced from Uniprot.org