| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CD232/PLXNC1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PLXNC1 |
| Gene ID: | 10154 |
| Uniprot ID: | PLXC1_HUMAN |
| Immunogen Region: | Ala35-Thr370 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8. |
| Protein Name | Plexin-C1Virus-Encoded Semaphorin Protein ReceptorCd Antigen Cd232 |
| Database Links | Reactome: R-HSA-416700 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Plexin-C1 proteinVirus-Encoded Semaphorin Protein Receptor proteinCd Antigen Cd232 proteinPLXNC1 proteinVESPR protein |
Information sourced from Uniprot.org