Human CD201/PROCR/EPCR protein (Recombinant-Active) (C-His) (STJP012323)

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STJP012323-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD201/PROCR/EPCR-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: PROCR
Gene ID: 10544
Uniprot ID: EPCR_HUMAN
Immunogen Region: Ser18-Ser210
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. A soluble form exists.probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
Function Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex.plays a role in the protein C pathway controlling blood coagulation.
Protein Name Endothelial Protein C Receptor
Activated Protein C Receptor
Apc Receptor
Endothelial Cell Protein C Receptor
Cd Antigen Cd201
Database Links Reactome: R-HSA-140875
Reactome: R-HSA-202733
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Endothelial Protein C Receptor protein
Activated Protein C Receptor protein
Apc Receptor protein
Endothelial Cell Protein C Receptor protein
Cd Antigen Cd201 protein
PROCR protein
EPCR protein

Information sourced from Uniprot.org

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