• Human CD200R1 protein (Active Recombinant) (C-hFc&His) (STJP001358)
  • Human CD200R1 protein (Active Recombinant) (C-hFc&His) (STJP001358)
  • Human CD200R1 protein (Active Recombinant) (C-hFc&His) (STJP001358)
  • Human CD200R1 protein (Active Recombinant) (C-hFc&His) (STJP001358)

Human CD200R1 protein (Active Recombinant) (C-hFc&His) (STJP001358)

SKU:
STJP001358

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Active Recombinant-Human CD200R1-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Human CD200 at 2 Mu g/mL (100 Mu L/well) can bind Human CD200 R with a linear range of 0.058-8.34 ng/mL.
Gene Symbol: CD200R1
Gene ID: 131450
Uniprot ID: MO2R1_HUMAN
Immunogen: Recombinant Human CD200R1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala27-Leu266) of human CD200R/MOX2R (Accession #NP_620161.1) fused with a Fc, 6×His tag at the C-terminus.
Function Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Protein Name Cell Surface Glycoprotein Cd200 Receptor 1
Cd200 Cell Surface Glycoprotein Receptor
Cell Surface Glycoprotein Ox2 Receptor 1
Database Links Reactome: R-HSA-198933
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 4: Cell Membrane
Isoform 2: Secreted
Isoform 3: Secreted
Alternative Protein Names Cell Surface Glycoprotein Cd200 Receptor 1 protein
Cd200 Cell Surface Glycoprotein Receptor protein
Cell Surface Glycoprotein Ox2 Receptor 1 protein
CD200R1 protein
CD200R protein
CRTR2 protein
MOX2R protein
OX2R protein
UNQ2522 protein
PRO6015 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance