Human CD20/MS4A1 protein (Recombinant-Active) (C-Flag) (STJP012461)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human CD20/MS4A1-C-Flag protein was developed from mammalian cells and has a target region of C-Flag. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 50mM HEPES, 150mM NaCl, 0.06% DDM, 0.012% CHS, 10% Glycerol, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | MS4A1 |
| Gene ID | 931 |
| Uniprot ID | CD20_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro297 |
Additional Info
| Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
| Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Protein Name | B-Lymphocyte Antigen Cd20B-Lymphocyte Surface Antigen B1Bp35Leukocyte Surface Antigen Leu-16Membrane-Spanning 4-Domains Subfamily A Member 1Cd Antigen Cd20 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLipid-AnchorConstitutively Associated With Membrane Rafts |
| Alternative Protein Names | B-Lymphocyte Antigen Cd20 proteinB-Lymphocyte Surface Antigen B1 proteinBp35 proteinLeukocyte Surface Antigen Leu-16 proteinMembrane-Spanning 4-Domains Subfamily A Member 1 proteinCd Antigen Cd20 proteinMS4A1 proteinCD20 protein |
Information sourced from Uniprot.org