| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CD172g/SIRPG-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | SIRPG |
| Gene ID: | 55423 |
| Uniprot ID: | SIRPG_HUMAN |
| Immunogen Region: | Glu29-Pro360 |
| Immunogen: | Homo sapiens (Human) |
| Function | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. |
| Protein Name | Signal-Regulatory Protein GammaSirp-GammaCd172 Antigen-Like Family Member BSignal-Regulatory Protein Beta-2Sirp-B2Sirp-Beta-2Cd Antigen Cd172g |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-391160 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Signal-Regulatory Protein Gamma proteinSirp-Gamma proteinCd172 Antigen-Like Family Member B proteinSignal-Regulatory Protein Beta-2 proteinSirp-B2 proteinSirp-Beta-2 proteinCd Antigen Cd172g proteinSIRPG proteinSIRPB2 protein |
Information sourced from Uniprot.org