Human CD172b/SIRPB1 protein (Recombinant) (C-His) (STJP006990)

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STJP006990
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD172b/SIRPB1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SIRPB1
Gene ID: 10326
Uniprot ID: SIRB1_HUMAN
Immunogen Region: Met1-Ala369
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Protein Name Signal-Regulatory Protein Beta-1
Sirp-Beta-1
Cd172 Antigen-Like Family Member B
Cd Antigen Cd172b
Database Links Reactome: R-HSA-2172127
Reactome: R-HSA-391160
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Signal-Regulatory Protein Beta-1 protein
Sirp-Beta-1 protein
Cd172 Antigen-Like Family Member B protein
Cd Antigen Cd172b protein
SIRPB1 protein

Information sourced from Uniprot.org

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