| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CD170/SIGLEC5-C-His-Flag-Fc protein was developed from mammalian cells and has a target region of C-His-Flag-Fc. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM Histidine, 10% Trehalose, 2% Mannitol, 50mM NaCl, 0.05% Tween 80, pH 5.5. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | SIGLEC5 |
| Gene ID: | 8778 |
| Uniprot ID: | SIGL5_HUMAN |
| Immunogen Region: | Glu17-Thr434 |
| Immunogen: | Homo sapiens (Human) |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 5Siglec-5Cd33 Antigen-Like 2Obesity-Binding Protein 2Ob-Bp2Ob-Binding Protein 2Cd Antigen Cd170 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Sialic Acid-Binding Ig-Like Lectin 5 proteinSiglec-5 proteinCd33 Antigen-Like 2 proteinObesity-Binding Protein 2 proteinOb-Bp2 proteinOb-Binding Protein 2 proteinCd Antigen Cd170 proteinSIGLEC5 proteinCD33L2 proteinOBBP2 protein |
Information sourced from Uniprot.org