| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human CD157 (BST1)-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: |
BST1 |
| Gene ID: |
683 |
| Uniprot ID: |
BST1_HUMAN |
| Immunogen Region: |
ECD |
| Immunogen: |
Optimized DNA sequence encoding Human extracellular domain of human ADP-ribosyl cyclase CD157including a C-terminal 6His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed in various tissues including placenta, lung, liver and kidney. |
| Function | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable). |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2Adp-Ribosyl Cyclase 2Bone Marrow Stromal Cell Antigen 1Bst-1Cyclic Adp-Ribose Hydrolase 2Cadpr Hydrolase 2Cd Antigen Cd157 |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196807Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 proteinAdp-Ribosyl Cyclase 2 proteinBone Marrow Stromal Cell Antigen 1 proteinBst-1 proteinCyclic Adp-Ribose Hydrolase 2 proteinCadpr Hydrolase 2 proteinCd Antigen Cd157 proteinBST1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
