Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human CD142/F3/TF-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | F3 |
Gene ID: | 2152 |
Uniprot ID: | TF_HUMAN |
Immunogen Region: | Met1-Glu251 |
Immunogen: | Homo sapiens (Human) |
Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The TF:VIIa complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
Protein Name | Tissue FactorTfCoagulation Factor IiiThromboplastinCd Antigen Cd142 |
Database Links | Reactome: R-HSA-140834Reactome: R-HSA-9031628 |
Cellular Localisation | Isoform 1: MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
Alternative Protein Names | Tissue Factor proteinTf proteinCoagulation Factor Iii proteinThromboplastin proteinCd Antigen Cd142 proteinF3 protein |
Information sourced from Uniprot.org