Name: Human CD131/CSF2RB protein (Recombinant) (N-His) (STJP010584)
SKU: STJP010584
Availability: InStock

Human CD131/CSF2RB protein (Recombinant) (N-His) (STJP010584)

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STJP010584

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human CD131/CSF2RB-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name	Cytokine Receptor Common Subunit Beta Cdw131 Gm-Csf/Il-3/Il-5 Receptor Common Beta Subunit Cd Antigen Cd131
Database Links	Reactome: R-HSA-512988 Reactome: R-HSA-5673001 Reactome: R-HSA-5683826 Reactome: R-HSA-5688849 Reactome: R-HSA-5688890 Reactome: R-HSA-912526
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Cytokine Receptor Common Subunit Beta protein Cdw131 protein Gm-Csf/Il-3/Il-5 Receptor Common Beta Subunit protein Cd Antigen Cd131 protein CSF2RB protein IL3RB protein IL5RB protein

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJP009273	Human CD131/CSF2RB protein (Recombinant) (C-His) (STJP009273)	Mammalian Cells
STJP011969	Human CD131/CSF2RB protein (Recombinant-Active) (C-His) (STJP011969)	Mammalian Cells
STJP002966	Human IL-3R Beta/CSF2RB/CD131 protein (Recombinant) (No tag) (STJP002966)	E.coli
STJA0027072	Anti-CD131/CSF2RB antibody [SAA1388] (STJA0027072)	Mouse	Monoclonal	Human	FC
STJA0027719	Anti-CD131/CSF2RB antibody [SAA1389] (STJA0027719)	Mouse	Monoclonal	Human	FC

Human CD131/CSF2RB protein (Recombinant) (N-His) (STJP010584)

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