Human CD123/IL3RA protein (Recombinant-Active) (C-His) (STJP011943)

SKU:
STJP011943-100
€691.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD123/IL3RA-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IL3RA
Gene ID: 3563
Uniprot ID: IL3RA_HUMAN
Immunogen Region: Lys20-Arg305
Immunogen: Homo sapiens (Human)
Function Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.
Protein Name Interleukin-3 Receptor Subunit Alpha
Il-3 Receptor Subunit Alpha
Il-3r Subunit Alpha
Il-3r-Alpha
Il-3ra
Cd Antigen Cd123
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-3 Receptor Subunit Alpha protein
Il-3 Receptor Subunit Alpha protein
Il-3r Subunit Alpha protein
Il-3r-Alpha protein
Il-3ra protein
Cd Antigen Cd123 protein
IL3RA protein
IL3R protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP004446 Human CD123/IL3RA protein (Recombinant) (C-His) (STJP004446) Mammalian Cells
STJP007268 Human CD123/IL3RA protein (Recombinant) (N-His) (STJP007268) E. coli
STJP009804 Mouse CD123/IL3RA protein (Recombinant) (N-His) (STJP009804) E. coli
STJP000897 Human IL-3RA/CD123 protein (Recombinant) (C-His) (STJP000897) HEK293 cells
STJP000982 Human EGFR protein (Active Recombinant) (C-His) (STJP000982) HEK293 cells

Related Products

!