Name: Human CCND2 protein (Recombinant) (N-His) (STJP004522)
SKU: STJP004522
Availability: InStock

Human CCND2 protein (Recombinant) (N-His) (STJP004522)

SKU:

STJP004522

£208.50 - £1,163.50

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Short Description :	Recombinant-Human CCND2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
Protein Name	G1/S-Specific Cyclin-D2
Database Links	Reactome: R-HSA-69231 Reactome: R-HSA-8934593 Reactome: R-HSA-9661069 Reactome: R-HSA-9754119
Cellular Localisation	Nucleus Cytoplasm Nucleus Membrane Cyclin D-Cdk4 Complexes Accumulate At The Nuclear Membrane And Are Then Translocated Into The Nucleus Through Interaction With Kip/Cip Family Members Isoform 2: Cytoplasm
Alternative Protein Names	G1/S-Specific Cyclin-D2 protein CCND2 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP017465	Human CCND2 protein (Recombinant) (His-Tag) (STJP017465)	E.coli	SDS-PAGE
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP015118	Human TAS1R1 protein protein (Recombinant) (N-His) (STJP015118)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP014345	Human HBZ protein (Recombinant) (N-His) (STJP014345)	E.coli	ELISA/WB

Human CCND2 protein (Recombinant) (N-His) (STJP004522)

General Information