Human CCN4 protein (Recombinant) (N-His) (STJP003424)

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STJP003424
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCN4-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCN4
Gene ID: 8840
Uniprot ID: CCN4_HUMAN
Immunogen Region: Cys216-Arg347
Immunogen: Homo sapiens (Human)
Function Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
Protein Name Ccn Family Member 4
Wnt1-Inducible-Signaling Pathway Protein 1
Wisp-1
Wnt-1-Induced Secreted Protein
Cellular Localisation Secreted
Alternative Protein Names Ccn Family Member 4 protein
Wnt1-Inducible-Signaling Pathway Protein 1 protein
Wisp-1 protein
Wnt-1-Induced Secreted Protein protein
CCN4 protein
WISP1 protein

Information sourced from Uniprot.org