Name: Human CCL4/MIP-1-beta protein (Recombinant) (N-GST) (STJP006575)
SKU: STJP006575
Availability: InStock

Human CCL4/MIP-1-beta protein (Recombinant) (N-GST) (STJP006575)

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STJP006575

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human CCL4/MIP-1-beta-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Protein Name	C-C Motif Chemokine 4 G-26 T-Lymphocyte-Secreted Protein Hc21 Lymphocyte Activation Gene 1 Protein Lag-1 Mip-1-Beta(1-69 Macrophage Inflammatory Protein 1-Beta Mip-1-Beta Pat 744 Protein H400 Sis-Gamma Small-Inducible Cytokine A4 T-Cell Activation Protein 2 Act-2 Cleaved Into - Mip-1-Beta(3-69
Database Links	Reactome: R-HSA-380108 Reactome: R-HSA-418594 Reactome: R-HSA-6783783
Cellular Localisation	Secreted
Alternative Protein Names	C-C Motif Chemokine 4 protein G-26 T-Lymphocyte-Secreted Protein protein Hc21 protein Lymphocyte Activation Gene 1 Protein protein Lag-1 protein Mip-1-Beta(1-69 protein Macrophage Inflammatory Protein 1-Beta protein Mip-1-Beta protein Pat 744 protein Protein H400 protein Sis-Gamma protein Small-Inducible Cytokine A4 protein T-Cell Activation Protein 2 protein Act-2 Cleaved Into - Mip-1-Beta(3-69 protein CCL4 protein LAG1 protein MIP1B protein SCYA4 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP009065	Mouse CCL4/MIP-1-beta protein (Recombinant) (N-His-SUMO) (STJP009065)	E. coli
STJP011374	Human CCL19/MIP-3-beta protein (Recombinant) (N-GST & C-His) (STJP011374)	E. coli
STJP003943	Human CCL3/MIP-1-alpha protein (Recombinant) (N-GST) (STJP003943)	E. coli
STJP002985	Mouse CCL4/MIP-1 Beta protein (Recombinant) (C-hFc) (STJP002985)	HEK293 cells
STJP004970	Human CCL23/MIP-3/MPIF-1 protein (Recombinant) (N-GST) (STJP004970)	E. coli

Human CCL4/MIP-1-beta protein (Recombinant) (N-GST) (STJP006575)

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