| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 1 EU/Mu g |
| Gene Symbol: |
CCL3L1.CCL3L3 |
| Gene ID: |
414062/6349 |
| Uniprot ID: |
CL3L1_HUMAN |
| Immunogen Region: |
Ala24-Ala93 |
| Immunogen: |
Recombinant Human CCL3L1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala24-Ala93) of human CCL3L1 (Accession #NP_001001437.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: |
AFDSTWKVDRSENYDKFMEK MGVNIVKRKLAAHDNLKLTI TQEGNKFTVKESSTFRNIEV VFELGVTFNYNLADGTELRG TWSLEGNKLIGKFKRTDNGN ELNTVREIIGDELVQTYVYE GVEAKRIFKKD |
| Post Translational Modifications | The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4. |
| Function | Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. |
| Protein Name | C-C Motif Chemokine 3-Like 1G0/G1 Switch Regulatory Protein 19-2Ld78-Beta(1-70Pat 464.2Small-Inducible Cytokine A3-Like 1Tonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 3-Like 1 proteinG0/G1 Switch Regulatory Protein 19-2 proteinLd78-Beta(1-70 proteinPat 464.2 proteinSmall-Inducible Cytokine A3-Like 1 proteinTonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70 proteinCCL3L1 proteinD17S1718 proteinG0S19-2 proteinSCYA3L1.CCL3L3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
