Human CCL3/MIP-1 alpha protein (Recombinant) (C-His) (STJP002836)

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STJP002836
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.1 EU/Mu g
Gene Symbol: CCL3
Gene ID: 6348
Uniprot ID: CCL3_HUMAN
Immunogen Region: Ala23-Ala92
Immunogen: Recombinant Human CCL3/MIP-1 alpha Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala23-Ala92) of human CCL3/MIP-1 alpha (Accession #NP_002974.1) fused with and a 6×His tag at the C-terminus.
Immunogen Sequence: ASLAADTPTACCFSYTSRQI PQNFIADYFETSSQCSKPGV IFLTKRSRQVCADPSEEWVQ KYVSDLELSA
Function Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Protein Name C-C Motif Chemokine 3
G0/G1 Switch Regulatory Protein 19-1
Macrophage Inflammatory Protein 1-Alpha
Mip-1-Alpha
Pat 464.1
Sis-Beta
Small-Inducible Cytokine A3
Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69
Ld78-Alpha(4-69
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-6783783
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 3 protein
G0/G1 Switch Regulatory Protein 19-1 protein
Macrophage Inflammatory Protein 1-Alpha protein
Mip-1-Alpha protein
Pat 464.1 protein
Sis-Beta protein
Small-Inducible Cytokine A3 protein
Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 protein
Ld78-Alpha(4-69 protein
CCL3 protein
G0S19-1 protein
MIP1A protein
SCYA3 protein

Information sourced from Uniprot.org

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