Human CCL28/MEC protein (Recombinant) (His-Tag) (STJP016529)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP016529
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General Information

Short DescriptionRecombinant-Human CCL28/MEC-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 10mM Sodium Citrate buffer (pH 3.5) containing 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin< 1 EU per 1ug of protein (determined by LAL method)

Target Information

Gene SymbolCCL28
Gene ID56477
Uniprot IDCCL28_HUMAN
Accession NumberNP_683513
ImmunogenHuman
Immunogen Region23-127aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MILPIASSCC TEVSHHISRR LLERVNMCRI QRADGDCDLA AVILHVKRRR ICVSPHNHTV KQWMKVQAAK KNGKGNVCHR KKHHGKRNSN RAHQGKHETY GHKTPY

Additional Info

Tissue Specificity Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.
Function Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
Protein Name C-C Motif Chemokine 28
Mucosae-Associated Epithelial Chemokine
Mec
Protein Cck1
Small-Inducible Cytokine A28
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 28 protein
Mucosae-Associated Epithelial Chemokine protein
Mec protein
Protein Cck1 protein
Small-Inducible Cytokine A28 protein
CCL28 protein
SCYA28 protein

Information sourced from Uniprot.org

Citations

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