| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | CCL24 |
| Gene ID: | 6369 |
| Uniprot ID: | CCL24_HUMAN |
| Immunogen: | Recombinant Human CCL24/Eotaxin-2 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Val27-Cys119) of human CCL24/Eotaxin-2 (Accession #O00175) fused with no additional amino acid. |
| Immunogen Region: | Val27-Cys119 |
| Immunogen Sequence: | VDAFLGTWKLVDSKNFDDYM KSLGVGFATRQVASMTKPTT IIEKNGDILTLKTHSTFKNT EISFKLGVEFDETTADDRKV KSIVTLDGGKLVHLQKWDGQ ETTLVRELIDGKLILTLTHG TAVCTRTYEKEA |
| Tissue Specificity | Activated monocytes and activated T lymphocytes. |
| Post Translational Modifications | N-glycosylated. |
| Function | Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. |
| Protein Name | C-C Motif Chemokine 24Ck-Beta-6Eosinophil Chemotactic Protein 2Eotaxin-2Myeloid Progenitor Inhibitory Factor 2Mpif-2Small-Inducible Cytokine A24 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 24 proteinCk-Beta-6 proteinEosinophil Chemotactic Protein 2 proteinEotaxin-2 proteinMyeloid Progenitor Inhibitory Factor 2 proteinMpif-2 proteinSmall-Inducible Cytokine A24 proteinCCL24 proteinMPIF2 proteinSCYA24 protein |
Information sourced from Uniprot.org
