Human CCL21/6Ckine protein (Recombinant) (N-His) (STJP003164)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CCL21/6Ckine-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CCL21 |
| Gene ID | 6366 |
| Uniprot ID | CCL21_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser24-Pro134 |
Additional Info
| Function | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Protein Name | C-C Motif Chemokine 216ckineBeta-Chemokine Exodus-2Secondary Lymphoid-Tissue ChemokineSlcSmall-Inducible Cytokine A21 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 21 protein6ckine proteinBeta-Chemokine Exodus-2 proteinSecondary Lymphoid-Tissue Chemokine proteinSlc proteinSmall-Inducible Cytokine A21 proteinCCL21 proteinSCYA21 proteinUNQ784 proteinPRO1600 protein |
Information sourced from Uniprot.org