| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CBS-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | CBS |
| Gene ID: | 102724560/875 |
| Uniprot ID: | CBS_HUMAN |
| Immunogen Region: | Lys72-Lys551 |
| Immunogen: | Homo sapiens (Human) |
| Function | Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons. |
| Protein Name | Cystathionine Beta-SynthaseBeta-ThionaseSerine Sulfhydrase |
| Database Links | Reactome: R-HSA-1614603Reactome: R-HSA-2408508 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Cystathionine Beta-Synthase proteinBeta-Thionase proteinSerine Sulfhydrase proteinCBS protein |
Information sourced from Uniprot.org