Human CBS protein (Recombinant) (N-His) (STJP007341)

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STJP007341
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CBS-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CBS
Gene ID: 102724560/875
Uniprot ID: CBS_HUMAN
Immunogen Region: Lys72-Lys551
Immunogen: Homo sapiens (Human)
Function Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.
Protein Name Cystathionine Beta-Synthase
Beta-Thionase
Serine Sulfhydrase
Database Links Reactome: R-HSA-1614603
Reactome: R-HSA-2408508
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names Cystathionine Beta-Synthase protein
Beta-Thionase protein
Serine Sulfhydrase protein
CBS protein

Information sourced from Uniprot.org

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