Human CBR3 protein (Recombinant) (N-His) (STJP003381)

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STJP003381
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CBR3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CBR3
Gene ID: 874
Uniprot ID: CBR3_HUMAN
Immunogen Region: Met1-Trp277
Immunogen: Homo sapiens (Human)
Function Catalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols. Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such as isatin or on the anticancer drug oracin. Best substrates for CBR3 is 1,2- naphthoquinone, hence could play a role in protection against cytotoxicity of exogenous quinones. Exerts activity toward ortho-quinones but not paraquinones. No endogenous substrate for CBR3 except isatin has been identified.
Protein Name Carbonyl Reductase Nadph 3
Nadph-Dependent Carbonyl Reductase 3
Quinone Reductase Cbr3
Short Chain Dehydrogenase/Reductase Family 21c Member 2
Database Links Reactome: R-HSA-211945
Cellular Localisation Cytoplasm
Alternative Protein Names Carbonyl Reductase Nadph 3 protein
Nadph-Dependent Carbonyl Reductase 3 protein
Quinone Reductase Cbr3 protein
Short Chain Dehydrogenase/Reductase Family 21c Member 2 protein
CBR3 protein
SDR21C2 protein

Information sourced from Uniprot.org

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