Human CBR3 (Carbonyl Reductase 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014104)
SPECIFICATIONS
General Information
| Short Description | This CBR3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.066ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | CBR3 |
| Gene ID | 874 |
| Uniprot ID | CBR3_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. |
| Post Translational Modifications | |
| Function | Catalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols. Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such as isatin or on the anticancer drug oracin. Best substrates for CBR3 is 1,2- naphthoquinone, hence could play a role in protection against cytotoxicity of exogenous quinones. Exerts activity toward ortho-quinones but not paraquinones. No endogenous substrate for CBR3 except isatin has been identified. |
| Protein Name | Carbonyl Reductase Nadph 3Nadph-Dependent Carbonyl Reductase 3Quinone Reductase Cbr3Short Chain Dehydrogenase/Reductase Family 21c Member 2 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Carbonyl Reductase Nadph 3 ELISA kitNadph-Dependent Carbonyl Reductase 3 ELISA kitQuinone Reductase Cbr3 ELISA kitShort Chain Dehydrogenase/Reductase Family 21c Member 2 ELISA kitCBR3 ELISA kitSDR21C2 ELISA kit |
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Information sourced from Uniprot.org