| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Carbonic anhydrase IX-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: |
Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
The activity was tested by its esterase activity, the measured activity is 15 pmole/ug/min NA |
| Gene Symbol: |
CA9 |
| Gene ID: |
768 |
| Uniprot ID: |
CAH9_HUMAN |
| Immunogen Region: |
ECD |
| Immunogen: |
Optimized DNA sequence encoding extracellular domain of human Carbonic anhydrase IX (GLN38-ASP414) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa. |
| Post Translational Modifications | Asn-346 bears high-mannose type glycan structures. |
| Function | Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). |
| Protein Name | Carbonic Anhydrase 9Carbonate Dehydratase IxCarbonic Anhydrase IxCa-IxCaixMembrane Antigen MnP54/58nRenal Cell Carcinoma-Associated Antigen G250Rcc-Associated Antigen G250Pmw1 |
| Database Links | Reactome: R-HSA-1234158Reactome: R-HSA-1475029 |
| Cellular Localisation | NucleusNucleolusCell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillus MembraneFound On The Surface Microvilli And In The NucleusParticularly In Nucleolus |
| Alternative Protein Names | Carbonic Anhydrase 9 proteinCarbonate Dehydratase Ix proteinCarbonic Anhydrase Ix proteinCa-Ix proteinCaix proteinMembrane Antigen Mn proteinP54/58n proteinRenal Cell Carcinoma-Associated Antigen G250 proteinRcc-Associated Antigen G250 proteinPmw1 proteinCA9 proteinG250 proteinMN protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
