Human Carbonic anhydrase IX protein (Recombinant) (STJP000615)

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STJP000615
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Carbonic anhydrase IX-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity: The activity was tested by its esterase activity, the measured activity is 15 pmole/ug/min NA
Gene Symbol: CA9
Gene ID: 768
Uniprot ID: CAH9_HUMAN
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding extracellular domain of human Carbonic anhydrase IX (GLN38-ASP414) including a C-terminal His tag was expressed in HEK293 cells. NA
Tissue Specificity Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
Post Translational Modifications Asn-346 bears high-mannose type glycan structures.
Function Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).
Protein Name Carbonic Anhydrase 9
Carbonate Dehydratase Ix
Carbonic Anhydrase Ix
Ca-Ix
Caix
Membrane Antigen Mn
P54/58n
Renal Cell Carcinoma-Associated Antigen G250
Rcc-Associated Antigen G250
Pmw1
Database Links Reactome: R-HSA-1234158
Reactome: R-HSA-1475029
Cellular Localisation Nucleus
Nucleolus
Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Microvillus Membrane
Found On The Surface Microvilli And In The Nucleus
Particularly In Nucleolus
Alternative Protein Names Carbonic Anhydrase 9 protein
Carbonate Dehydratase Ix protein
Carbonic Anhydrase Ix protein
Ca-Ix protein
Caix protein
Membrane Antigen Mn protein
P54/58n protein
Renal Cell Carcinoma-Associated Antigen G250 protein
Rcc-Associated Antigen G250 protein
Pmw1 protein
CA9 protein
G250 protein
MN protein

Information sourced from Uniprot.org

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