Tissue Specificity | |
Post Translational Modifications | O-linked glycans are assumed to be the Glc-Gal disaccharides typically found as secondary modifications of hydroxylated lysines in collagen-like domains. |
Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Protein Name | Complement C1q Subcomponent Subunit A |
Database Links | Reactome: R-HSA-166663Reactome: R-HSA-173623Reactome: R-HSA-977606 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Complement C1q Subcomponent Subunit A ELISA kitC1QA ELISA kit |
output | |
Information sourced from Uniprot.org