• Biotinylated Human BTLA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human BTLA is greater than 95% as determined by SEC-HPLC
  • Immobilized Anti-BTLA Antibody, hFc Tag at 0. 5 Mu g/ml (100 Mu l/well) on the plate. Dose response curve for Biotinylated Human BTLA, His Tag with the EC50 of 8. 0ng/ml determined by ELISA.

Human BTLA protein (Recombinant) (C-His-Avi) {Biotin} (STJP001573)

SKU:
STJP001573

£618.50 - £1,909.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human BTLA-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: BTLA
Gene ID: 151888
Uniprot ID: BTLA_HUMAN
Immunogen Region: Lys31-Ser150
Immunogen: DNA sequence encoding Human BTLA including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells.
Protein Name B- And T-Lymphocyte Attenuator
B- And T-Lymphocyte-Associated Protein
Cd Antigen Cd272
Database Links Reactome: R-HSA-388841
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names B- And T-Lymphocyte Attenuator protein
B- And T-Lymphocyte-Associated Protein protein
Cd Antigen Cd272 protein
BTLA protein

Information sourced from Uniprot.org

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