Human BMP3/Osteogenin protein (Recombinant) (N-His) (STJP004045)

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STJP004045
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human BMP3/Osteogenin-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: BMP3
Gene ID: 651
Uniprot ID: BMP3_HUMAN
Immunogen Region: Gln363-Arg472
Immunogen: Homo sapiens (Human)
Function Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentiation and ossification. Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways.
Protein Name Bone Morphogenetic Protein 3
Bmp-3
Bone Morphogenetic Protein 3a
Bmp-3a
Osteogenin
Cellular Localisation Secreted
Alternative Protein Names Bone Morphogenetic Protein 3 protein
Bmp-3 protein
Bone Morphogenetic Protein 3a protein
Bmp-3a protein
Osteogenin protein
BMP3 protein
BMP3A protein

Information sourced from Uniprot.org

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