Human BLVRA protein (Recombinant) (N-His) (STJP004912)

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STJP004912
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human BLVRA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: BLVRA
Gene ID: 644
Uniprot ID: BIEA_HUMAN
Immunogen Region: Met1-His125
Immunogen: Homo sapiens (Human)
Function Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Does not reduce bilirubin IXbeta. Uses the reactants NADH or NADPH depending on the pH.NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7). NADPH, however, is the probable reactant in biological systems.
Protein Name Biliverdin Reductase A
Bvr A
Biliverdin-Ix Alpha-Reductase
Database Links Reactome: R-HSA-189483
Reactome: R-HSA-9707564
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Biliverdin Reductase A protein
Bvr A protein
Biliverdin-Ix Alpha-Reductase protein
BLVRA protein
BLVR protein
BVR protein

Information sourced from Uniprot.org