| Short Description : | Recombinant-Human BLVRA-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 100mM NaCl, 50% Glycerol, pH 8.0. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | BLVRA |
| Gene ID: | 644 |
| Uniprot ID: | BIEA_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Glu6-Ser294 |
| Function | Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Does not reduce bilirubin IXbeta. Uses the reactants NADH or NADPH depending on the pH.NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7). NADPH, however, is the probable reactant in biological systems. |
| Protein Name | Biliverdin Reductase ABvr ABiliverdin-Ix Alpha-Reductase |
| Database Links | Reactome: R-HSA-189483Reactome: R-HSA-9707564 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Biliverdin Reductase A proteinBvr A proteinBiliverdin-Ix Alpha-Reductase proteinBLVRA proteinBLVR proteinBVR protein |
Information sourced from Uniprot.org