Human BIN2 (Bridging Integrator 2) Sandwich ELISA Kit Kit (STJE0007478)

Human BIN2 (Bridging Integrator 2) Sandwich ELISA Kit Kit (STJE0007478)

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STJE0007478
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.112ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This BIN2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: BIN2
Gene ID: 51411
Uniprot ID: BIN2_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in natural killer cells (at protein level). Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
Post Translational Modifications
Function Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.
Protein Name Bridging Integrator 2
Breast Cancer-Associated Protein 1
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-9673768
Cellular Localisation Cytoplasm
Cell Projection
Podosome Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cell Cortex
Phagocytic Cup
Associates With Membranes Enriched In Phosphoinositides
Detected In The Actin-Rich Cell Cortex At The Leading Edge Of Migrating Cells
Detected At Podosomes
At An Actin-Rich Ring-Like Structure
Alternative ELISA Names Bridging Integrator 2 ELISA kit
Breast Cancer-Associated Protein 1 ELISA kit
BIN2 ELISA kit
BRAP1 ELISA kit
output

Information sourced from Uniprot.org

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